Quality of Life and Late Complications After Minimally Invasive Compared to Open Esophagectomy: Results of a Randomized TrialReport as inadecuate




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World Journal of Surgery

, Volume 39, Issue 8, pp 1986–1993

First Online: 03 June 2015

Abstract

BackgroundThe minimally invasive esophagectomy MIE is widely being implemented for esophageal cancer in order to reduce morbidity and improve quality of life. Non-randomized studies investigating the mid-term quality of life after MIE show conflicting results at 1-year follow-up. Therefore, the aim of this study is to determine whether MIE has a continuing better mid-term 1-year quality of life than open esophagectomy OE indicating both a faster recovery and less procedure-related symptoms.

MethodsA one-year follow-up analysis of the quality of life was conducted for patients participating in the randomized trial in which MIE was compared with OE. Late complications as symptomatic stenosis of anastomosis are also reported.

ResultsQuality of life at 1 year was better in the MIE group than in the OE group for the physical component summary SF36 50 6; 48–53 versus 45 9; 42–48 p .003; global health C30 79 10; 76–83 versus 67 21; 60–75 p .004; and pain OES18 module 6 9; 2–8 versus 16 16; 10–22 p .001, respectively. Twenty six patients 44 % in the MIE and 22 patients 39 % in the OE group were diagnosed and treated for symptomatic stenosis of the anastomosis.

ConclusionsThis first randomized trial shows that MIE is associated with a better mid-term one-year quality of life compared to OE.

On behalf of the TIME-trial study Group.

Other members of the TIME-trial study group are co-authors of this study and can be found under the heading collaborators in Appendix.

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Author: K. W. Maas - M. A. Cuesta - M. I. van Berge Henegouwen - J. Roig - L. Bonavina - C. Rosman - S. S. Gisbertz - S. S. 

Source: https://link.springer.com/article/10.1007/s00268-015-3100-y







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