Laparoscopic antireflux surgery increases health-related quality of life in children with GERDReport as inadecuate

Laparoscopic antireflux surgery increases health-related quality of life in children with GERD - Download this document for free, or read online. Document in PDF available to download.

Surgical Endoscopy

, Volume 31, Issue 8, pp 3122–3129

First Online: 18 November 2016Received: 04 May 2016Accepted: 02 November 2016


IntroductionImproving health-related quality of life HRQoL is increasingly recognized as an essential part of patient care outcome. Little is known about the effect of laparoscopic antireflux surgery LARS on the HRQoL in the pediatric patients. The aims of this study were to evaluate the effect of LARS on HRQoL in children with gastroesophageal reflux disease GERD and to identify predictors that influence HRQoL outcome after LARS.

MethodsBetween 2011 and 2013, 25 patients with therapy-resistant GERD median age 6 2–18 years were included prospectively. Caregivers and children with normal neurodevelopment >4 years were asked to fill out the validated PedsQL 4.0 Generic Core Scales before and 3–4 months after LARS.

ResultsThe PedsQL was completed by all caregivers n = 25 and 12 children. HRQoL total score improved significantly after LARS, both from a parental p = 0.009 and child’s perspective p = 0.018. The psychosocial health summary and physical health summary scores also improved significantly after LARS. HRQoL before and after LARS was significantly lower in children with impaired neurodevelopment p < 0.001. However, neurodevelopment did not influence the effect of LARS on HRQoL. The only significant predictor for improvement in HRQoL after LARS was age at the time of operation p = 0.001.

ConclusionsHRQoL significantly improves after LARS. Although children with impaired neurodevelopment had lower overall HRQoL, neurodevelopment by itself does not predict inferior improvement in HRQoL after LARS. Older children have a more favorable HRQoL outcome after LARS compared to younger children. This may suggest caution when considering LARS in younger GERD patients.

KeywordsPediatric Children Reflux GERD Fundoplication Quality of life Antireflux surgery  Download fulltext PDF

Author: Femke A. Mauritz - Rebecca K. Stellato - L. W. Ernst van Heurn - Peter D. Siersema - Cornelius E. J. Sloots - Roderic


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