A reduced-order modeling for efficient design study of artificial valve in enlarged ventricular outflow tractsReport as inadecuate




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1 WIAS - Weierstrass Institute for Applied Analysis and Stochastics 2 IMFT - Institut de mécanique des fluides de Toulouse 3 REO - Numerical simulation of biological flows LJLL - Laboratoire Jacques-Louis Lions, Inria Paris-Rocquencourt, UPMC - Université Pierre et Marie Curie - Paris 6

Abstract : A computational approach is proposed for efficient design study of a reducer stent to be percutaneously implanted in enlarged right ventricular outflow tracts RVOT. The need for such a device is driven by the absence of bovine or artificial valves which could be implanted in these RVOT to replace the absent or incompetent native valve, as is often the case over time after Tetralogy of Fallot repair. Hemodynamics are simulated in the stented RVOT via a reduce order model based on proper orthogonal decomposition, while the artificial valve is modeled as a thin resistive surface. The reduced order model is obtained from the numerical solution on a reference device configuration, then varying the geometrical parameters diameter for design purposes. To validate the approach, forces exerted on the valve and on the reducer are monitored, varying with geometrical parameters, and compared with the results of full CFD simulations. Such an approach could also be useful for uncertainty quantification.

Keywords : percutaneous pulmonary valve replacement finite element method Device design blood flow CFD proper orthogonal decomposition POD repaired Tetralogy of Fallot





Author: Alfonso Caiazzo - Romain Guibert - Irene E. Vignon-Clementel -

Source: https://hal.archives-ouvertes.fr/



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