Performance of population specific job exposure matrices JEMs: European collaborative analyses on occupational risk factors for chronic obstructive pulmonary disease with job exposure matrices ECOJEM.Report as inadecuate




Performance of population specific job exposure matrices JEMs: European collaborative analyses on occupational risk factors for chronic obstructive pulmonary disease with job exposure matrices ECOJEM. - Download this document for free, or read online. Document in PDF available to download.

* Corresponding author 1 Recherche en épidémiologie et biostatistique 2 Department of Thoracic Medicine 3 Environmental and Occupational Health Group 4 Ocupational Hygiene Program 5 Department Epidemiology

Abstract : OBJECTIVES: To compare the performance of population specific job exposure matrices JEMs and self reported occupational exposure with data on exposure and lung function from three European general populations. METHODS: Self reported occupational exposure yes or no and present occupation were recorded in the three general population surveys conducted in France, The Netherlands, and Norway. Analysis was performed on subjects, aged 25-64, who provided good forced expiratory volume in 1 second FEV1 tracings and whose occupations were performed by at least two people, in the French 6217 men and 5571 women, the Dutch men from urban 854 and rural 780 areas, and the Norwegian 395 men surveys. Two population specific JEMs, based on the percentage of subjects who reported themselves exposed in each job, were constructed for each survey and each sex. The first matrix classified jobs into three categories of exposure according to the proportion of subjects who reported themselves exposed in each job P10-50 JEM, low < 10%, moderate 10-49%, high > or = 50%. For the second matrix, a dichotomous variable was constructed to have the same statistical power as the self reported exposure-that is, the exposure prevalence p was the same with both exposure assessment methods Pp JEM. Relations between occupational exposure, as estimated by the two JEMs and self reported exposure, and age, height, city, and smoking adjusted FEV1 score were compared. RESULTS: Significant associations between occupational exposure estimated by the population specific JEM and lung function were found in the French and the rural Dutch surveys, whereas no significant relation was found with self reported exposure. In populations with few subjects in most jobs, exposure cannot be estimated with sufficient precision by a population specific JEM, which may explain the lack of relation in the Norwegian and the Dutch urban area surveys. CONCLUSION: The population specific JEM, which was easy to construct and cost little, seemed to perform better than crude self reported exposures, in populations with sufficient numbers of subjects per job.

Mots-clés : Job exposure matrix Occupational exposure Lung function





Author: Nicole Le Moual - Per Bakke - Ewa Orlowski - Dick Heederik - H. Kromhout - S. M. Kennedy - Bert Rijcken - Francine Kauffmann -

Source: https://hal.archives-ouvertes.fr/



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