T-staging of rectal cancer: accuracy of 3.0 Tesla MRI compared with 1.5 TeslaReport as inadecuate

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Abdominal Imaging

, Volume 37, Issue 3, pp 475–481

First Online: 15 June 2011


ObjectivesMagnetic resonance imaging MRI is not accurate in discriminating T1-2 from borderline T3 rectal tumors. Higher resolution on 3 Tesla-3T-MRI could improve diagnostic performance for T-staging. The aim of this study was to determine whether 3T-MRI compared with 1.5 Tesla-1.5T-MRI improves the accuracy for the discrimination between T1-2 and borderline T3 rectal tumors and to evaluate reproducibility.

Methods13 patients with non-locally advanced rectal cancer underwent imaging with both 1.5T and 3T-MRI. Three readers with different expertise evaluated the images and predicted T-stage with a confidence level score. Receiver operator characteristics curves with areas under the curve AUC and diagnostic parameters were calculated. Inter- and intra-observer agreements were calculated with quadratic kappa-weighting. Histology was the reference standard.

ResultsSeven patients had pT1-2 tumors and six had pT3 tumors. AUCs ranged from 0.66 to 0.87 at 1.5T vs. 0.52–0.82 at 3T. Mean overstaging rate was 43% at 1.5T and 57% at 3T P = 0.23. Inter-observer agreement was κ 0.50–0.71 at 1.5T vs. 0.15–0.68 at 3T. Intra-observer agreement was κ 0.71 at 1.5T and 0.76 at 3T.

ConclusionsThis is the first study to compare 3T with 1.5T MRI for T-staging of rectal cancer within the same patients. Our results showed no difference between 3T and 1.5T-MRI for the distinction between T1-2 and borderline T3 tumors, regardless of expertise. The higher resolution at 3T-MRI did not aid in the distinction between desmoplasia in T1-2-tumors and tumor stranding in T3-tumors. Larger studies are needed to acknowledge these findings.

KeywordsRectal cancer MRI T-stage 3 Tesla  Download fulltext PDF

Author: Monique Maas - Doenja M. J. Lambregts - Max J. Lahaye - Geerard L. Beets - Walter Backes - Roy F. A. Vliegen - Margree

Source: https://link.springer.com/


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