Nonsurgical Corrective Union of Osteoporotic Vertebral Fracture with Once-Weekly TeriparatideReport as inadecuate




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Case Reports in Orthopedics - Volume 2015 2015, Article ID 784360, 3 pages -

Case Report

Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan

Igarashi Memorial Hospital, 1-17-23 Tsuchizakiminato-Chuo, Akita 011-0946, Japan

Received 17 May 2015; Accepted 26 July 2015

Academic Editor: Stamatios A. Papadakis

Copyright © 2015 Naohisa Miyakoshi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Osteoporotic vertebral fractures usually heal with kyphotic deformities with subsidence of the vertebral body when treated conservatively. Corrective vertebral union using only antiosteoporotic pharmacotherapy without surgical intervention has not been reported previously. An 81-year-old female with osteoporosis presented with symptomatic fresh L1 vertebral fracture with intravertebral cleft. Segmental vertebral kyphosis angle VKA at L1 was 20° at diagnosis. Once-weekly teriparatide administration, hospitalized rest, and application of a thoracolumbosacral orthosis alleviated symptoms within 2 months. Corrective union of the affected vertebra was obtained with these treatments. VKA at 2 months after injury was 8° correction, 12° and was maintained as of the latest follow-up at 7 months. Teriparatide has potent bone-forming effects and has thus been expected to enhance fracture healing. Based on the clinical experience of this case, teriparatide may have the potential to allow correction of unstable vertebral fractures without surgical intervention.





Author: Naohisa Miyakoshi, Akira Horikawa, and Yoichi Shimada

Source: https://www.hindawi.com/



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