Incidence rate of symptomatic venous thromboembolic disease in patients from a medical care program in Buenos Aires, Argentina: a prospective cohortReport as inadecuate




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Thrombosis Journal

, 11:16

First Online: 01 August 2013Received: 12 May 2013Accepted: 05 July 2013

Abstract

BackgroundThe incidence of venous thromboembolic disease VTED is estimated to be, on average, 1–2 cases per 1,000 individuals per year worldwide. There are few data concerning the incidence rate IR of VTED in the Argentinean population at large.

Our aim was to estimate the IR of VTED at the Italian Hospital Medical Care Program IHMCP in Buenos Aires, the most populous city in Argentina.

MethodsThis prospective cohort study evaluated all consecutive incident cases of pulmonary thromboembolism PTE and deep vein thrombosis DVT confirmed in patients over the age of 17 who were members of the IHMCP from June 2006 to May 2012. Any patient who had an initial confirmed VTED episode and was a member of the IHMCP at the time of diagnosis was considered an incident case.

ResultsThere were 1,138 cases of VTED for 687,871 person-years of follow-up. The crude IR of VTED was 1.65 95% CI: 1.56 to 1.75 per 1,000 person-years. The highest IR was found in subjects >80 years old 5.92 per 1,000 person years; 95% CI: 5.41 to 6.49.

The IRs adjusted to the population of the city of Buenos Aires were 0.90 95% CI: 0.84 to 0.95 for VTED, 0.71 95% CI: 0.66 to 0.76 for DVT, and 0.34 95% CI: 0.31 to 0.37 for PTE.

ConclusionsVTED is a common health problem with a high IR in members of the IHMCP, especially the elderly. This is the first paper to report prospectively the cumulative incidence of VTED in Latin America.

KeywordsEpidemiology Incidence Pulmonary embolism Venous thromboembolism Venous thrombosis Electronic supplementary materialThe online version of this article doi:10.1186-1477-9560-11-16 contains supplementary material, which is available to authorized users.

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Source: https://link.springer.com/article/10.1186/1477-9560-11-16







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