Relation of left atrial peak systolic strain with left ventricular diastolic dysfunction and brain natriuretic peptide level in patients presenting with ST-elevation myocardial infarctionReport as inadecuate




Relation of left atrial peak systolic strain with left ventricular diastolic dysfunction and brain natriuretic peptide level in patients presenting with ST-elevation myocardial infarction - Download this document for free, or read online. Document in PDF available to download.

Cardiovascular Ultrasound

, 11:24

First Online: 05 July 2013Received: 06 March 2013Accepted: 04 June 2013

Abstract

BackgroundIn patients presenting with ST-elevation myocardial infarction STEMI, we investigated the relation of left atrial LA deformational parameters evaluated by two-dimensional speckle tracking imaging 2D-STI with conventional echocardiographic diastolic dysfunction parameters and B-type natriuretic peptide BNP level.

MethodsNinety STEMI patients who were treated with primary percutaneous coronary intervention PCI and 22 healthy control subjects were enrolled. STEMI patients had echocardiographic examination 48 hours after the PCI procedure and venous blood samples were drawn simultaneously. In addition to conventional echocardiographic parameters, LA strain curves were obtained for each patient. Average peak LA strain values during left ventricular LV systole LAs-strain were measured.

ResultsBNP values were higher in MI patients compared to controls. Mean LAs-strain in control group was higher than MI group 30.6 ± 5.6% vs. 21.6 ± 6.6%; p = 0.001. LAs-strain had significant correlation with LVEF r = 0.51, p = 0.001, also significant inverse correlations between LAs-strain and BNP level r = −0.41, p = 0.001, E-Em r = −0.30, p = 0.001, LA maximal volume r = −0.41, p = 0.001, LA minimal volume r = −0.50, p = 0.001 and LV end systolic volume r = −0.37, p = 0.001 were detected. The cut off value of LAs-strain to predict BNP > 100 pg-ml was determined as 19.9% with 55.3% sensitivity and 77.2% specificity p < 0.05 AUC:0.7.

ConclusionOur study showed that LAs-strain values decreased consistently with deteriorating systolic and diastolic function in STEMI patients treated with primary PCI. LA-s strain measurements may be helpful as a complimentary method to evaluate diastolic function in this patient population.

KeywordsAcute myocardial infarction Left atrial strain Brain natriuretic peptide Diastolic dysfunction Electronic supplementary materialThe online version of this article doi:10.1186-1476-7120-11-24 contains supplementary material, which is available to authorized users.

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Author: Cem Dogan - Nihal Ozdemir - Suzan Hatipoglu - Ruken Bengi Bakal - Mehmet Onur Omaygenc - Baris Dindar - Ozkan Candan - Me

Source: https://link.springer.com/



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