The clinical profile of Kawasaki disease of children from three Polish centers: a retrospective studyReport as inadecuate




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Rheumatology International

, Volume 34, Issue 6, pp 875–880

First Online: 28 July 2013Received: 01 March 2013Accepted: 16 July 2013

Abstract

Kawasaki disease KD is one of the most common vasculitides of childhood. The aim of this retrospective study is to determine the incidence of KD and to evaluate its presenting symptoms, clinical course, laboratory tests, and treatment in patients with complete KD and incomplete KD at three pediatric rheumatology centers in Poland from January 2011 to December 2012. A total of 27 Caucasian children 12 boys and 15 girls with median age of 3 years range 4 months–12 years were included in this study. The incidence of complete versus incomplete KD was 17 63 % versus 10 37 % children, respectively. Patients with incomplete KD significantly less presented cervical lymphadenopathy 20 vs. 88.2 %; p = 0.00075, changes in extremities 30 vs. 76.5 %; p = 0.04, and bilateral nonpurulent conjunctivitis 60 vs. 100 %; p = 0.01. Cardiac assessments show that the majority of patients with KD have not got coronary artery aneurysms CAA. The median time from the onset of symptoms to intravenous immunoglobulin IVIG infusion was 7 days for complete KD and 11 days for incomplete KD. IVIG delay in the incomplete KD had no effect on the incidence of CAA. In conclusion, there were no differences in demographic features, age of onset, and laboratory tests of patients with complete and incomplete KD. Patients with incomplete KD significantly rarely presented cervical lymphadenopathy, changes in extremities, and conjunctival injection. Electrocardiography is a sensitive test to recognize cardiac involvement in the acute phase of KD. Despite the fact that incomplete forms of presentation often delay diagnosis, in most patients treatment with IVIG can avoid complication of CAA.

KeywordsKawasaki disease Children Incomplete Kawasaki Coronary artery aneurysms  Download fulltext PDF



Author: Daiva Gorczyca - Jacek Postępski - Edyta Olesińska - Małgorzata Lubieniecka - Iwona Lachór-Motyka - Violetta Opoka-Winia

Source: https://link.springer.com/







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