Mueller matrix polarimetry for improved liver fibrosis diagnosisReport as inadecuate

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1 LSOL - Laboratoire de Spectrométrie et Optique Laser 2 departement de pathologie

Abstract : An experimental Mueller matrix polarimeter is used to quantify human liver fibrosis by measuring retardance and depolarization of thin biopsies. The former parameter is sensitive to fibrillar collagen, the latter is specifically sensitive to fibrillar collagen around blood vessels, which is not significant for liver fibrosis diagnosis. By using depolarization like a filter, retardance distribution enables to distinguish between disease stages and limit the high degree of observer discrepancy

Keywords : optics polarimetry polarimetric imaging biomedical optics tissue polarimetry Mueller matrix

Author: Matthieu Dubreuil - P. Babilotte - Martin Loïc - David Sevrain - Sylvain Rivet - Yann Le Grand - Guy Le Brun - Bruno Turlin - Be



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