Metastatic Secondary Fibrosarcoma of Bone Responsive to Repeated Courses of Ifosfamide and Associated With HypoglycemiaReport as inadecuate




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Sarcoma - Volume 7 2003, Issue 2, Pages 81-85

Case Report

Department of Medical Oncology, London Regional Cancer Centre, 399 Royal Avenue, Kelowna, BC, London V1Y 5L3, Canada

Division of Endocrinology, Department of Medicine, St. Joseph-s Hospital, Ontario, London, Canada



Copyright © 2003 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We present a case of a 40-year-old man with secondary fibrosarcoma of bone, arising from a non-ossifying fibroma. Hesubsequently developed metastatic disease that responded to four successive chemotherapy courses, the last three using thesame dose-schedule of single agent ifosfamide. Eventual rapid progression of a huge intra-abdominal mass was associatedwith the syndrome of extrapancreatic tumour hypoglycemia EPTH. The clinicopathological behaviour of fibrosarcoma ofbone, and the mechanism of EPTH are discussed.





Author: Elaine S. Bouttell, N. Wilson Rodger, and Vivien H. C. Bramwell

Source: https://www.hindawi.com/



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