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BioMed Research International - Volume 2014 2014, Article ID 959461, 13 pages -

Review Article

Department of Physiology, Michigan State University, East Lansing, MI 48824, USA

Cellular and Molecular Biology Graduate Program, Michigan State University, East Lansing, MI 48824, USA

Center for Integrative Toxicology, Michigan State University, East Lansing, MI 48824, USA

Received 10 June 2014; Accepted 16 June 2014; Published 2 July 2014

Academic Editor: Yiguo Jiang

Copyright © 2014 Aaron L. Oom et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

First discovered in 1993, microRNAs miRNAs have been one of the hottest research areas over the past two decades. Oftentimes, miRNAs levels are found to be dysregulated in cancer patients. The potential use of miRNAs in cancer therapies is an emerging and promising field, with research finding miRNAs to play a role in cancer initiation, tumor growth, and metastasis. Therefore, miRNAs could become an integral part from cancer diagnosis to treatment in future. This review aims to examine current novel research work on the potential roles of miRNAs in cancer therapies, while also discussing several current challenges and needed future research.





Author: Aaron L. Oom, Brock A. Humphries, and Chengfeng Yang

Source: https://www.hindawi.com/



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