Intranasal inoculation of sows with highly pathogenic porcine reproductive and respiratory syndrome virus at mid-gestation causes transplacental infection of fetusesReport as inadecuate




Intranasal inoculation of sows with highly pathogenic porcine reproductive and respiratory syndrome virus at mid-gestation causes transplacental infection of fetuses - Download this document for free, or read online. Document in PDF available to download.

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Abstract : AbstractTransplacental infection plays a critical role in the reproductive failure induced by porcine reproductive and respiratory syndrome virus PRRSV, yet exposure of sows and gilts to classical PRRSV generally leads to reproductive failure after 85 days of gestation. We report, for the first time, that the susceptibility of fetuses to highly pathogenic PRRSV HP-PRRSV is similar at 60 days and 90 days of gestation. This difference from classical PRRSV may contribute to its high pathogenicity. A field study of the HP-PRRSV vaccine in pregnant sows at mid-gestation should be considered.





Author: Tongtong Wang Xiaofei Wang Xin-An Li Li Nie Minxia Zhang Sidang Liu Xiaomin Zhao Yingli Shang En-Min Zhou Julian A. Hiscox Yihong

Source: https://hal.archives-ouvertes.fr/



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