Misdiagnosis of narcolepsyReport as inadecuate




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Sleep and Breathing

, Volume 20, Issue 4, pp 1277–1284

First Online: 23 June 2016Received: 04 November 2015Revised: 16 May 2016Accepted: 23 May 2016

Abstract

BackgroundNarcolepsy is a chronic primary sleep disorder, characterized by excessive daytime sleepiness and sleep dysfunction with or without cataplexy. Narcolepsy is uncommon, with a low prevalence rate which makes it difficult to diagnose definitively without a complex series of tests and a detailed history. The aim of this study was to review patients referred to a tertiary sleep centre who had been labelled with a diagnosis of narcolepsy prior to referral in order to assess if the diagnosis was accurate, and if not, to determine the cause of diagnostic misattribution.

MethodsAll patients seen at a sleep centre from 2007–2013 n = 551 who underwent detailed objective testing including an MSLT PSG, as well as wearing an actigraphy watch and completing a sleep diary for 2 weeks, were assessed for a pre-referral and final diagnosis of narcolepsy.

ResultsOf the 41 directly referred patients with a diagnostic label of narcolepsy, 19 46 % were subsequently confirmed to have narcolepsy on objective testing and assessment by a sleep physician using ICSD-2 criteria.

ConclusionsThe diagnosis of narcolepsy was incorrectly attributed to almost 50 % of patients labelled with a diagnosis of narcolepsy who were referred for further opinion by a variety of specialists and generalists. Accurate diagnosis of narcolepsy is critical for many reasons, such as the impact it has on quality of life, driving, employment, insurance and pregnancy in women as well as medication management.

KeywordsNarcolepsy Diagnosis Misdiagnosis Cataplexy MSLT  Download fulltext PDF



Author: Laura Dunne - Pallavi Patel - Emily L Maschauer - Ian Morrison - Renata L Riha

Source: https://link.springer.com/article/10.1007/s11325-016-1365-5







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