Gold-catalyzed synthesis of enantioenriched furfurylamines from amino acidsReport as inadecuate




Gold-catalyzed synthesis of enantioenriched furfurylamines from amino acids - Download this document for free, or read online. Document in PDF available to download.

* Corresponding author 1 ISCR - Institut des Sciences Chimiques de Rennes

Abstract : A convenient gold-catalyzed asymmetric synthesis of polysubstituted furfurylamines starting from amino acids has been achieved. The cyclization proceeded under mild conditions and generally provided the furan or iodofuran derivatives in good to excellent yields and with high enantiomeric excess. Iodofurans were validated as good intermediates for classical organometallic coupling reactions.





Author: Benjamin Guieu - Myriam Le Roch - Michèle David - Nicolas Gouault -

Source: https://hal.archives-ouvertes.fr/



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