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Chinese Science Bulletin

, Volume 57, Issue 5, pp 450–454

First Online: 21 January 2012Received: 16 April 2011Accepted: 09 June 2011


Photodynamic therapy PDT is a very effective treatment for port wine stains PWS. To guide and assess PDT treatment, a handheld optical coherence tomography OCT probe was designed for real-time imaging of the PWS patient. The system uses a light source with a center wavelength of 1310 nm, −3 dB bandwidth of 90 nm and an optical power of 9 mW. The system also has a spatial resolution of 8 μm lateral × 7 μm axial, an imaging rate of 4 frames per second, and a 102 dB sensitivity. We then demonstrate that the OCT imaging system can clearly distinguish between normal and PWS tissues. Therefore, the system can provide valuable guidance for PDT treatment.

Keywordsoptical coherence tomography photodynamic therapy port-wine stain These authors contributed equally to this work

This article is published with open access at Springerlink.com

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Author: TianShi Wang - ChengMing Wang - NaiYan Huang - Jian Zhang - Ying Gu - Ping Xue

Source: https://link.springer.com/article/10.1007/s11434-011-4864-6


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