A novel role for microglia in minimizing excitotoxicityReport as inadecuate

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BMC Biology

, 10:7

First Online: 31 January 2012Received: 27 January 2012Accepted: 31 January 2012


Microglia are the abundant, resident myeloid cells of the central nervous system CNS that become rapidly activated in response to injury or inflammation. While most studies of microglia focus on this phenomenon, little is known about the function of -resting- microglia, which possess fine, branching cellular processes. Biber and colleagues, in a recent paper in Journal of Neuroinflammation, report that ramified microglia can limit excitotoxicity, an important insight for understanding mechanisms that limit neuron death in CNS disease.

See research articlehttp:-www.jneuroinflammation.com-content-9-1-27.

Electronic supplementary materialThe online version of this article doi:10.1186-1741-7007-10-7 contains supplementary material, which is available to authorized users.

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Author: Mariko L Howe - Ben A Barres

Source: https://link.springer.com/article/10.1186/1741-7007-10-7

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