en fr Effects of Omega-3 fatty acids on cardioprotection: Omega-3 fatty acids profile in rats and in patients with cardioverter implantable defibrillator Effets des acides gras Oméga-3 sur la Cardioprotection: Etude des acides gReport as inadecuate




en fr Effects of Omega-3 fatty acids on cardioprotection: Omega-3 fatty acids profile in rats and in patients with cardioverter implantable defibrillator Effets des acides gras Oméga-3 sur la Cardioprotection: Etude des acides g - Download this document for free, or read online. Document in PDF available to download.

1 PRETA TIMC-IMAG - Techniques de l-Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications Grenoble

Abstract : Although the Mediterranean diet MED is considered the optimal diet to prevent coronary heart disease CHD, it is still unknown whether adoption of MED may result in improved myocardial resistance to ischemia-reperfusion injury and may potentially prevent ventricular arrhythmias. Accordingly, the first experimental study was carried out to investigate whether a diet low in saturated fats and omega-6 fatty acids ω6 but rich in plant and marine omega-3 fatty acids ω3, a typical MED fatty acid profile, may result in smaller infarct size and better left ventricular function LVF recovery in a rat model of regional ischemia-reperfusion. Results demonstrate a great accumulation of ω3 and a parallel decrease of arachidonic acid in plasma, cell membranes and cardiac mitochondria. Also, the MED rats developed smaller infarct size compared with the control groups p



Author: Sabrina Zeghichi -

Source: https://hal.archives-ouvertes.fr/



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