An Ex Vivo Model in Human Femoral Heads for Histopathological Study and Resonance Frequency Analysis of Dental Implant Primary StabilityReport as inadecuate




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BioMed Research InternationalVolume 2014 2014, Article ID 535929, 8 pages

Research Article

Department of Traumatology and Orthopedic Surgery, “San Cecilio” Clinical Hospital, University of Granada, Spain

Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA

Oral Surgery and Implant Dentistry Department, School of Dentistry, University of Granada, Granada, Spain

Department of Experimental Psychology, School of Psychology, University of Granada, Granada, Spain

Department of Periodontics, School of Dentistry, University of Granada, Granada, Spain

Department of Pathology, School of Medicine and Institute of Biopathology and Regenerative Medicine IBIMER, University of Granada, Granada, Spain

Departamento de Anatomía Patológica, Facultad de Medicina, 18012 Granada, Spain

Received 21 January 2014; Revised 12 May 2014; Accepted 19 May 2014; Published 4 June 2014

Academic Editor: Konstantinos Michalakis

Copyright © 2014 Pedro Hernández-Cortés et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. This study was designed to explore relationships of resonance frequency analysis RFA—assessed implant stability ISQ values with bone morphometric parameters and bone quality in an ex vivo model of dental implants placed in human femoral heads and to evaluate the usefulness of this model for dental implant studies. Material and Methods. This ex vivo study included femoral heads from 17 patients undergoing surgery for femoral neck fracture due to osteoporosis OP or for total prosthesis joint replacement due to severe hip osteoarthrosis OA . Sixty  mm Dentsply Astra implants were placed, followed by RFA. CD44 immunohistochemical analysis for osteocytes was also carried out. Results. As expected, the analysis yielded significant effects of femoral head type OA versus OA , but not of the implants or of the interaction of the two factors . Bonferroni post hoc comparisons showed a lower mean ISQ for implants in decalcified heads than in fresh or fixated heads both . The ISQ score fresh was significantly higher for those in OA versus OP heads. However, mixed linear analysis showed no significant association between ISQ scores and morphologic or histomorphometric results in all cases, and no significant differences in ISQ values were found as a function of the length or area of the cortical layer both . Conclusion. Although RFA-determined ISQ values are not correlated with morphometric parameters, they can discriminate bone quality OP versus OA. This ex vivo model is useful for dental implant studies.





Author: Pedro Hernández-Cortés, Alberto Monje, Pablo Galindo-Moreno, Andrés Catena, Inmaculada Ortega-Oller, José Salas-Pérez, 

Source: https://www.hindawi.com/



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