A novel human coronavirus: Middle East respiratory syndrome human coronavirusReport as inadecuate




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Science China Life Sciences

, Volume 56, Issue 8, pp 683–687

First Online: 07 August 2013Received: 25 May 2013Accepted: 15 June 2013DOI: 10.1007-s11427-013-4519-8

Cite this article as: Geng, H. & Tan, W. Sci. China Life Sci. 2013 56: 683. doi:10.1007-s11427-013-4519-8

Abstract

In 2012, a novel coronavirus, initially named as human coronavirus EMC HCoV-EMC but recently renamed as Middle East respiratory syndrome human coronavirus MERS-CoV, was identified in patients who suffered severe acute respiratory infection and subsequent renal failure that resulted in death. Ongoing epidemiological investigations together with retrospective studies have found 61 laboratory-confirmed cases of infection with this novel coronavirus, including 34 deaths to date. This novel coronavirus is culturable and two complete genome sequences are now available. Furthermore, molecular detection and indirect immunofluorescence assay have been developed. The present paper summarises the limited recent advances of this novel human coronavirus, including its discovery, genomic characterisation and detection.

KeywordsHCoV-EMC MERS-CoV genomic characterisation molecular detection This article is published with open access at Springerlink.com

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Author: HeYuan Geng - WenJie Tan

Source: https://link.springer.com/







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