Haematological Profile and Intensity of Urogenital Schistosomiasis in Ghanaian ChildrenReport as inadecuate




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Journal of Environmental and Public Health - Volume 2017 2017, Article ID 4248325, 5 pages - https:-doi.org-10.1155-2017-4248325

Research Article

Department of Medical Laboratory Technology, University of Cape Coast, Cape Coast, Ghana

Department of Biochemistry, University of Cape Coast, Cape Coast, Ghana

Department of Mathematics and Science Education, University of Cape Coast, Cape Coast, Ghana

Correspondence should be addressed to Justice Afrifa

Received 12 March 2017; Accepted 28 May 2017; Published 21 June 2017

Academic Editor: Pauline E. Jolly

Copyright © 2017 Justice Afrifa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Urogenital schistosomiasis is a widely contracted parasitic helminth infection often associated with haematological abnormalities. Aim. We investigated the relationship between the haematological profile and the intensity of schistosomiasis among children in the Yeji district. Materials and Methods. A total of 100 participants comprising 50 Schistosoma haematobium S. haematobium infected and 50 noninfected controls aged 6–17 years matched for age and sex were recruited into the study. Blood and urine samples were collected and haematological profile and presence of S. haematobium eggs were assessed using standard protocols. Results. Haemoglobin HGB , haematocrit HCT , mean cell volume MCV , mean cell haemoglobin MCH , and mean cell haemoglobin concentration MCHC levels were reduced in cases compared to controls. Mixed cell percentage MXD and red blood cell distribution width RDW-CV were significantly elevated among cases as compared to controls. Haematuria was a clinical characteristic of heavy infection. Conclusion. S. haematobium infection creates an imbalance in the haematological profile. We found low HGB, HCT, MCV, MCH, and MCHC levels coupled with increased % MXD count and RDW-CV. Also, low MCV, MCH, and MCHC and high % MXD count are independently associated with S. haematobium infection among our study participants.





Author: Justice Afrifa, Desmond Gyedu, Eric Ofori Gyamerah, Samuel Essien-Baidoo, and Isaac Mensah-Essilfie

Source: https://www.hindawi.com/



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