Comparison of Laboratory Data of Acute Cholangitis Patients Treated with or without Immunosuppressive DrugsReport as inadecuate




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ISRN GastroenterologyVolume 2014 2014, Article ID 619628, 5 pages

Research Article

Department of Gastroenterology, National Hospital Organization Shimoshizu Hospital, 934-5 Shikawatashi, Yotsukaido City, Chiba 284-0003, Japan

Department of Radiology, National Hospital Organization Shimoshizu Hospital, 934-5 Shikawatashi, Yotsukaido City, Chiba 284-0003, Japan

Department of Surgery, National Hospital Organization Shimoshizu Hospital, 934-5 Shikawatashi, Yotsukaido City, Chiba 284-0003, Japan

Department of Neurology, National Hospital Organization Shimoshizu Hospital, 934-5 Shikawatashi, Yotsukaido City, Chiba 284-0003, Japan

Department of Rheumatology, National Hospital Organization Shimoshizu Hospital, 934-5 Shikawatashi, Yotsukaido City, Chiba 284-0003, Japan

Department of Pediatrics, National Hospital Organization Shimoshizu Hospital, 934-5 Shikawatashi, Yotsukaido City, Chiba 284-0003, Japan

Received 8 January 2014; Accepted 5 March 2014; Published 10 March 2014

Academic Editors: A. J. Karayiannakis, A. Mencarelli, and L. Rodrigo

Copyright © 2014 Minoru Tomizawa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. Symptoms and laboratory data between acute cholangitis AC patients treated with and AC patients treated without immunosuppressive drugs corticosteroids or methotrexate were compared to identify factors that can be meaningful to the diagnosis of AC. Methods. The Wilcoxon signed-rank test was used for comparison of baseline variables between the patients with AC treated with immunosuppressive drugs and those without it. The chi-squared test was used in the analysis of the symptoms. Results. In total, 69 patients with AC were enrolled. Fifteen patients were treated with immunosuppressants due to rheumatoid arthritis or other collagen diseases. Jaundice was less frequent in the patients treated with immunosuppressive drugs . T-Bil level was marginally lower in the patients treated with immunosuppressants . AST and ALT levels were lower in the patients treated with immunosuppressants and 0.022, respectively. Conclusions. The frequency of jaundice and AST and ALT levels were lower in the patients treated with immunosuppressive drugs. It is recommended that care be taken to evaluate jaundice, AST level, and ALT level in the diagnosis of AC.





Author: Minoru Tomizawa, Fuminobu Shinozaki, Rumiko Hasegawa, Yoshinori Shirai, Noboru Ichiki, Yasufumi Motoyoshi, Takao Sugiyama, 

Source: https://www.hindawi.com/



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