Differences in brain gene transcription profiles advocate for an important role of cognitive function in upstream migration and water obstacles crossing in European eelReport as inadecuate




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BMC Genomics

, 16:378

First Online: 12 May 2015Received: 05 December 2014Accepted: 27 April 2015DOI: 10.1186-s12864-015-1589-y

Cite this article as: Podgorniak, T., Milan, M., Pujolar, J.M. et al. BMC Genomics 2015 16: 378. doi:10.1186-s12864-015-1589-y

Abstract

BackgroundEuropean eel is a panmictic species, whose decline has been recorded since the last 20 years. Among human-induced environmental factors of decline, the impact of water dams during species migration is questioned. The main issue of this study was to pinpoint phenotypic traits that predisposed glass eels to successful passage by water barriers. The approach of the study was individual-centred and without any a priori hypothesis on traits involved in the putative obstacles selective pressure. We analyzed the transcription level of 14,913 genes.

ResultsTranscriptome analysis of three tissues brain, liver and muscle from individuals sampled on three successive forebays separated by water obstacles indicated different gene transcription profiles in brain between the two upstream forebays. No differences in gene transcription levels were observed in liver and muscle samples among segments. A total of 26 genes were differentially transcribed in brain. These genes encode for, among others, keratins, cytokeratins, calcium binding proteins S100 family, cofilin, calmodulin, claudin and thy-1 membrane glycoprotein. The functional analysis of these genes highlighted a putative role of cytoskeletal dynamics and synaptic plasticity in fish upstream migration.

ConclusionSynaptic connections in brain are solicited while eels are climbing the obstacles with poorly designed fishways. Successful passage by such barriers can be related to spatial learning and spatial orientation abilities when fish is out of the water.

KeywordsTranscripomics European eel Water dams Microarray Synaptic plasticity Fish brain Fabien Pierron and Francoise Daverat contributed equally to this work.

Electronic supplementary materialThe online version of this article doi:10.1186-s12864-015-1589-y contains supplementary material, which is available to authorized users.

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Author: Tomasz Podgorniak - Massimo Milan - Jose Marti Pujolar - Gregory E Maes - Luca Bargelloni - Eric De Oliveira - Fabien Pie

Source: https://link.springer.com/



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