Percutaneous Microwave Ablation in the Spleen for Treatment of Hypersplenism in Cirrhosis PatientsReport as inadecuate




Percutaneous Microwave Ablation in the Spleen for Treatment of Hypersplenism in Cirrhosis Patients - Download this document for free, or read online. Document in PDF available to download.

Digestive Diseases and Sciences

, Volume 61, Issue 1, pp 287–292

First Online: 02 June 2015Received: 27 February 2015Accepted: 23 May 2015DOI: 10.1007-s10620-015-3732-7

Cite this article as: Jiang, X., Gao, F., Ma, Y. et al. Dig Dis Sci 2016 61: 287. doi:10.1007-s10620-015-3732-7

Abstract

AimThe aim of this study was to estimate the feasibility and therapeutic effectiveness of percutaneous microwave ablation in the treatment of hypersplenism in cirrhosis.

MethodsForty-one cirrhosis patients with hypersplenism were treated with ultrasonography-guided percutaneous microwave ablation between February 2007 and August 2011. Peripheral blood cell counts, portal vein diameter, splenic vein diameter, and blood flow of splenic vein were evaluated before and after the operation, and complications of the treatment were also investigated. All patients were followed up for 24 months.

ResultsThe levels of platelets and white blood cells were increased, while the splenic vein diameter narrowed gradually after the therapy and 24 months later. Moreover, patients received percutaneous microwave ablation had much lower splenic venous flow velocity. The portal vein diameter did not change significantly 6 months after the treatment, although it narrowed gradually within 3 months after the treatment. Furthermore, no complications such as uncontrollable bleeding, splenic abscess, spleen rupture, and damage in surrounding organ happened after the therapy.

ConclusionsGraded percutaneous microwave ablation, as a minimally invasive therapy, could damage the spleen, increase the levels of platelets and white blood cells, and reduce portal hypertension effectively without serious complications. Percutaneous microwave ablation is an effective, safe, and feasible method for cirrhosis patients with hypersplenism.

KeywordsPercutaneous microwave ablation Cirrhosis Hypersplenism Minimally invasive therapy XiangWu Jiang and Fei Gao have contributed equally to this work.

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Author: XiangWu Jiang - Fei Gao - Yan Ma - ShuFen Feng - XueLian Liu - HongKe Zhou

Source: https://link.springer.com/







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