Current state of knowledge of hepatic encephalopathy part III: non-absorbable disaccharidesReport as inadecuate




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Metabolic Brain Disease

, Volume 31, Issue 6, pp 1361–1364

First Online: 16 September 2016Received: 28 June 2016Accepted: 05 September 2016DOI: 10.1007-s11011-016-9910-2

Cite this article as: Morgan, M.Y. Metab Brain Dis 2016 31: 1361. doi:10.1007-s11011-016-9910-2

Abstract

Nonabsorbable disaccharides have been the mainstay of treatment for hepatic encephalopathy since introduced into clinical practice in 1966. Their beneficial effects reflect their ability to reduce the intestinal production-absorption of ammonia. A recent Cochrane review confirmed the efficacy and safety of nonabsorbable disaccharides for the treatment and prevention of hepatic encephalopathy in patients with cirrhosis. The findings were robust and support the use of nonabsorbable disaccharides as a first line treatment for hepatic encephalopathy, in this patient population, and for its prevention.

KeywordsHepatic encephalopathy lactulose lactitol efficacy safety  Download fulltext PDF



Author: Marsha Y. Morgan

Source: https://link.springer.com/







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