Higher n3-fatty acid status is associated with lower risk of iron depletion among food insecure Canadian Inuit womenReport as inadecuate




Higher n3-fatty acid status is associated with lower risk of iron depletion among food insecure Canadian Inuit women - Download this document for free, or read online. Document in PDF available to download.

BMC Public Health

, 13:289

Global health

Abstract

BackgroundHigh rates of iron deficiency and anemia are common among Inuit and Arctic women despite a traditional diet based on animal source foods. However, representative data on iron status and relevant determinants for this population are lacking. The objectives were to determine the prevalence of anemia and depletion of iron stores, then to identify correlates of iron status in non-pregnant Canadian Inuit women.

MethodsIn a cross-sectional survey of 1550 women in the International Polar Year Inuit Health Survey, 2007-2008, hemoglobin, serum ferritin, soluble transferrin receptor on a subset, C-reactive protein CRP, RBC fatty acid composition, and H pylori serology were analyzed on fasting venous blood. Sociodemographic, food security status, anthropometric, dietary, and health data were collected. Correlates of iron status were assessed with multivariate linear and logistic models.

ResultsAnemia was observed in 21.7% and iron deficient erythropoiesis in 3.3% of women. For women with CRP ≤ 10 mg-L n = 1260 29.4% had depleted iron stores. Inadequate iron intakes were observed in 16% of premenopausal and <1% of postmenopausal women. Among food insecure women, higher long-chain n-3 polyunsaturated fatty acid LC-PUFA status, which reflects a more traditional food pattern, was associated with reduced risk of iron depletion.

ConclusionsIron depletion and anemia are a concern for Inuit women despite adequate total dietary iron intake primarily from heme sources. The high prevalence of H. pylori exposure, together with dietary iron adequacy, suggests an inflammation-driven iron deficiency and mild anemia. The anti-inflammatory properties of LC-PUFA may be important for iron status in this population.

AbbreviationsCANDATResearch orientated nutrient calculation system

CINECentre for Indigenous Peoples’ Nutrition and Environment

hs-CRPHigh-sensitivity C-reactive protein

IDIron deficiency

IDAIron deficiency anemia

IDEIron deficient erythropoiesis

ISRInuvialuit Settlement Region

LC-PUFALong-chain polyunsaturated fatty acids

MFMarket food

SFSerum ferritin

SIDESoftware for intake distribution estimation

sTfRSoluble transferrin receptor

TFTraditional food.

Electronic supplementary materialThe online version of this article doi:10.1186-1471-2458-13-289 contains supplementary material, which is available to authorized users.

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Author: Jennifer A Jamieson - Harriet V Kuhnlein - Hope A Weiler - Grace M Egeland

Source: https://link.springer.com/



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