Hypertriglyceridemia as a possible cause of coma: a case reportReport as inadecuate

Hypertriglyceridemia as a possible cause of coma: a case report - Download this document for free, or read online. Document in PDF available to download.

Journal of Medical Case Reports

, 6:412

First Online: 30 November 2012Received: 16 August 2012Accepted: 24 October 2012DOI: 10.1186-1752-1947-6-412

Cite this article as: Inokuchi, R., Matsumoto, A., Azihara, R. et al. J Med Case Reports 2012 6: 412. doi:10.1186-1752-1947-6-412


IntroductionMany studies suggest that elevated triglyceride levels are associated with increased long-term risk of stroke, including transient ischemic attacks. In addition, elevated triglyceride levels independently contribute to plasma viscosity and decreased blood flow. However, no consensus has been reached regarding the significance of hypertriglyceridemia as an independent risk factor for ischemic stroke.

Case presentationWe report the case of a patient admitted to our hospital for sudden onset of coma. Laboratory test results revealed he had high blood glucose 28.2mmol-L, high glycated hemoglobin 11.4 percent, considerably high serum triglyceride levels 171.5mmol-L; type V hyperlipoproteinemia, and high plasma viscosity 1.90mPa-s with normal β-hydroxybutyric acid levels. His triglyceride levels decreased after administering intravenous fluids. Our patient’s consciousness level improved gradually over three days. All serum lipid levels decreased seven days after admission.

ConclusionsThe findings in our patient’s case are likely explained by triglyceride-mediated hyperviscosity causing a transient ischemic attack. In the present report we suggest that when several tests do not reveal the cause of stroke-like symptoms, measurement of plasma viscosity may be informative.

KeywordsHypertriglyceridemia Plasma viscosity Alcohol Diabetes mellitus Transient ischemic attack Electronic supplementary materialThe online version of this article doi:10.1186-1752-1947-6-412 contains supplementary material, which is available to authorized users.

Download fulltext PDF

Author: Ryota Inokuchi - Akinori Matsumoto - Ryuta Azihara - Hajime Sato - Yoshibumi Kumada - Hideyuki Yokoyama - Megumi Okada - To

Source: https://link.springer.com/

Related documents