Erratum to “Involvement of Nrf2-Mediated Upregulation of Heme Oxygenase-1 in Mollugin-Induced Growth Inhibition and Apoptosis in Human Oral Cancer Cells”Report as inadecuate




Erratum to “Involvement of Nrf2-Mediated Upregulation of Heme Oxygenase-1 in Mollugin-Induced Growth Inhibition and Apoptosis in Human Oral Cancer Cells” - Download this document for free, or read online. Document in PDF available to download.

BioMed Research InternationalVolume 2014 2014, Article ID 386742, 3 pages

Erratum

Department of Maxillofacial Tissue Regeneration and Research Center for Tooth & Periodontal Regeneration, School of Dentistry, Kyung Hee University, Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Republic of Korea

Department of Oral Medicine, School of Dentistry, Kyung Hee University, Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Republic of Korea

Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyung Hee University, Hoegi-dong, Dongdaemun-gu, Seoul 130-701, Republic of Korea

College of Pharmacy, Yeungnam University, Gyeongsan 712-749, Republic of Korea

Received 1 May 2014; Accepted 20 May 2014; Published 14 July 2014

Copyright © 2014 Young-Man Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

In the original paper, there were a number of errors in Figures 4 and 7. Here, we provide the right form of these figures. In Figure 4a, p-JNK panels were the same in the HN4 and HN12 cells. In Figure 4d, vertical, light streaks were included in the p-JNK panel of HN4 during the scanning of X-ray film. In Figure 7c, vertical, light streaks were included in the NF-B p65 nuclear panel of HN4 during the scanning of X-ray film.

Figure 4: Effect of mollugin on phosphorylation of MAPK a, activation of Nrf2 b, and expression of HO-1 c in OSCCs. Effects of MAP kinase inhibitors on mollugin-induced activation of NF-B, Nrf2, and HO-1 d. Cells were treated with 40 μM mollugin for indicated times a–c. Cells were pretreated with the p38 inhibitor SB203580 20 μM-L, the ERK inhibitor PD98059 20 μM-L, or the JNK inhibitor SP600125 20 μM-L for 1 hour and treated with 40 μM mollugin for 30 min MAPK, Nrf2, and NF-B or 3 days HO-1. The results are representative of three independent experiments.Figure 7: Effect of Nrf2 siRNA on mollugin-induced growth inhibition a, apoptosis b, and apoptosis-related proteins expression c. Cells were treated with 40 μM mollugin for indicated times a. Cells were pretreated with Nrf2 siRNA 250 nM for 5 h and treated for 3 days with mollugin 40 μM a–c. Statistically significant difference as compared to control, .

Statistically significant difference as compared to mollugin, . Data are representative of 3 independent experiments.



Author: Young-Man Lee, Q-Schick Auh, Deok-Won Lee, Jun-Yeol Kim, Ha-Jin Jung, Seung-Ho Lee, and Eun-Cheol Kim

Source: https://www.hindawi.com/



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