Successful application of technetium-99m-labeled octreotide acetate scintigraphy in the detection of ectopic adrenocorticotropin-producing bronchial carcinoid lung tumor: a case reportReport as inadecuate




Successful application of technetium-99m-labeled octreotide acetate scintigraphy in the detection of ectopic adrenocorticotropin-producing bronchial carcinoid lung tumor: a case report - Download this document for free, or read online. Document in PDF available to download.

Journal of Medical Case Reports

, 4:323

First Online: 18 October 2010Received: 30 December 2009Accepted: 18 October 2010DOI: 10.1186-1752-1947-4-323

Cite this article as: Esfahani, A.F., Chavoshi, M., Noorani, M.H. et al. J Med Case Reports 2010 4: 323. doi:10.1186-1752-1947-4-323

Abstract

IntroductionThe diagnostic efficacy of somatostatin receptor scintigraphy labeling with 111 indium in the localization of tumors has been assessed in a limited number of patients with contradictory outcomes. Here, we describe the case of a patient with an ectopic adrenocorticotropic hormone-producing bronchial carcinoid tumor diagnosed preoperatively using technetium-99m-labeled octreotide acetate scintigraphy.

Case presentationA 29-year-old Asian man presented to our hospital with the typical clinical features of Cushing-s syndrome, which he had had for a duration of 18 months. The results of a biochemical evaluation revealed he had adrenocorticotropic hormone-dependent Cushing-s syndrome. The results of a spiral abdominal computed tomography scan showed he had bilateral adrenal hypertrophy. A magnetic resonance image of the patient-s brain showed he had a normal hypophysis. Whole body technetium-99m-labeled octreotide acetate scintigraphy was performed to check for the presence of an ectopic adrenocorticotropic hormone-producing tumor. The scan results showed a small focal increase in uptake in the lower lobe of our patient-s right lung, just above his diaphragm. A spiral chest computed tomography scan also revealed a small non-specific lesion in the same region. A transthoracic biopsy was then performed. Pathological evaluation confirmed the diagnosis of a carcinoid tumor, of the adrenocorticotropic hormone-producing type. After surgical removal, the patient-s symptoms resolved and significant clinical improvement was achieved.

ConclusionsThis case report shows that technetium-99m-labeled octreotide acetate scintigraphy can effectively detect an ectopic adrenocorticotropic hormone-producing bronchial carcinoid.

Electronic supplementary materialThe online version of this article doi:10.1186-1752-1947-4-323 contains supplementary material, which is available to authorized users.

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Author: Armaghan Fard Esfahani - Maryam Chavoshi - Mohammad Hadi Noorani - Mohsen Saghari - Mohammad Eftekhari - Davood Beiki - Ba

Source: https://link.springer.com/







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