Accuracy of the Hospital Anxiety and Depression Scale for Identifying Depression in Chronic Obstructive Pulmonary Disease PatientsReport as inadecuate




Accuracy of the Hospital Anxiety and Depression Scale for Identifying Depression in Chronic Obstructive Pulmonary Disease Patients - Download this document for free, or read online. Document in PDF available to download.

Pulmonary Medicine - Volume 2014 2014, Article ID 973858, 7 pages -

Research Article

Division of Pulmonology, University Hospital of Zurich, 8091 Zurich, Switzerland

Medical Sciences Department, Uppsala University, 75237 Uppsala, Sweden

Division of Pulmonology, Cantonal Hospital of Glarus, 8750 Glarus, Switzerland

Division of Pulmonology, Cantonal Hospital of St. Gallen, 9007 St. Gallen, Switzerland

Division of Pulmonology, Clinical Barmelweid, 5017 Barmelweid, Switzerland

Division of Pulmonology, Cantonal Hospital of Aarau, 5000 Aarau, Switzerland

University Clinic of Internal Medicine, Cantonal Hospital Baselland and University of Basel, 4031 Basel, Switzerland

Division of Pulmonology, Cantonal Hospital of Münsterlingen, 8596 Münsterlingen, Switzerland

Received 21 June 2014; Revised 12 November 2014; Accepted 20 November 2014; Published 4 December 2014

Academic Editor: Denis Caillaud

Copyright © 2014 Christoph Nowak et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Psychological morbidity is common in chronic respiratory diseases. The diagnostic accuracy of the Hospital Anxiety and Depression Scale HADS and risk factors for comorbid depression in chronic obstructive pulmonary disease COPD are addressed. Consecutive COPD patients GOLD stage I–IV, 40–75 years old were enrolled in a multicentre, cross-sectional cohort study. Diagnosis of depression was ascertained through clinical records. Lung function, HADS score, 6-minute walking test 6-MWT, MRC dyspnoea score, and COPD Assessment Test CAT were evaluated. Two hundred fifty-nine COPD patients mean age 62.5 years; 32% female; mean FEV1 48% predicted were included. Patients diagnosed with depression 29-259; 11.2% had significantly higher HADS-D and HADS-Total scores than nondepressed patients median quartiles HADS-D 6 4; 9 versus 4 2; 7, median HADS-Total 14 10; 20 versus 8 5; 14. Receiver-operating characteristic plots showed moderate accuracy for HADS-D, AUC 0.662 95%CI 0.601–0.719, and HADS-Total, AUC 0.681 95%CI 0.620–0.737, with optimal cut-off scores of >5 and >9, respectively. Sensitivity and specificity were 62.1% and 62.6% for HADS-D compared to 75.9% and 55.2% for HADS-Total. Age, comorbidities, sex, and lower airflow limitation predicted depression. The HADS exhibits low diagnostic accuracy for depression in COPD patients. Younger men with comorbidities are at increased risk for depression.





Author: Christoph Nowak, Noriane A. Sievi, Christian F. Clarenbach, Esther Irene Schwarz, Christian Schlatzer, Thomas Brack, Martin

Source: https://www.hindawi.com/



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