Myocardial adaptations in the failing heart: cause or consequenceReport as inadecuate

Myocardial adaptations in the failing heart: cause or consequence - Download this document for free, or read online. Document in PDF available to download.

Journal of Muscle Research and Cell Motility

, Volume 29, Issue 6–8, pp 159–162

First Online: 14 February 2009Received: 04 December 2008Accepted: 07 January 2009DOI: 10.1007-s10974-009-9169-x

Cite this article as: van Dijk, S.J., Hamdani, N., Stienen, G.J.M. et al. J Muscle Res Cell Motil 2008 29: 159. doi:10.1007-s10974-009-9169-x


Many changes in morphology, biochemical properties and myocyte function occur during development to heart failure. Most changes may be compensatory, yet unable to prevent cardiac dysfunction in the long run. This illustrates that it is important to carefully dissect the disease causing modifications from cardiac adaptation, in order to obtain a better understanding of the pathophysiological processes leading to heart failure.

KeywordsHeart failure Myocyte contractility Protein phosphorylation  Download fulltext PDF

Author: Sabine J. van Dijk - Nazha Hamdani - Ger J. M. Stienen - Jolanda van der Velden


Related documents