Nonislet Cell Tumor Hypoglycemia in a Patient with Adrenal Cortical CarcinomaReport as inadecuate




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Case Reports in Endocrinology - Volume 2016 2016, Article ID 5731417, 4 pages -

Case Report

Division of Endocrinology, Department of Internal Medicine, Sahmyook Medical Center, Seoul, Republic of Korea

Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea

Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea

Received 28 August 2016; Accepted 19 October 2016

Academic Editor: Michael P. Kane

Copyright © 2016 Se Won Kim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Nonislet cell tumor hypoglycemia NICTH is a rare but serious paraneoplastic syndrome in which a tumor secretes incompletely processed precursors of insulin-like growth factor-II IGF-II, causing hypoglycemia. Here, we report an exceptional case of NICTH caused by nonfunctioning adrenocortical carcinoma in a 39-year-old male with recurrent hypoglycemia. The patient’s serum IGF-II-IGF-I ratio had increased to 27.8. The serum level of the IGF-II-IGF-I ratio was normalized after removal of the tumor, and the hypoglycemic attacks no longer occurred after the operation.





Author: Se Won Kim, Seung-Eun Lee, Young Lyun Oh, Seokhwi Kim, Sun Hee Park, and Jae Hyeon Kim

Source: https://www.hindawi.com/



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