Experiencia de trombolisis sistematizada en infarto cerebral agudo en un hospital público de ChileReport as inadecuate




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Background: The only accepted treatment for acute ischemic stroke is thrombolysiswith recombinant tissue plasminogen activator t-PA. It was implementedin Chile in 1996, although its use was mainly restricted in Chile to private clinics.Recently, at year 2009, we have implemented this treatment in a public hospital. Aim:To describe the results of treatment of acute ischemic stroke with t-PA in a publichospital in Chile. Material and Methods: Prospective analysis of all eligible patientswith acute ischemic stroke that were admitted within 4 hours of its onset and hadno contraindications for thrombolysis. Results: In an eight months period, a total of19 intravenous thrombolyses were performed in 12 males and seven females aged 28to 79 years old. The mean lapse between onset of symptoms and onset of thrombolysiswas 190 ± 57 min. Results were favorable, according to Rankin and NationalInstitute of Health Stroke scales. Ninety days after treatment, 63% of patients hadminimal or absent disability, 26% had moderate disability and only one 5% hadsevere disability. One patient had a clinically not signifi cant intracranial hemorrhageand one patient died six days after thrombolysis. Conclusions: These results indicatethat thrombolysis can be successfully implemented in Chilean public hospitals. Thelimitations for its use in this setting are mostly administrative.



Author: Figueroa Reyes, Tatiana; - Sáez Méndez, David; - Nogales Gaete, Jorge; - Mansilla, Eloy; - Sánchez V., Rodrigo; - Delgado B.,

Source: http://repositorio.uchile.cl/



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