Effect of haemoglobin concentration on the clinical outcomes in patients with acute myocardial infarction and the factors related to haemoglobinReport as inadecuate




Effect of haemoglobin concentration on the clinical outcomes in patients with acute myocardial infarction and the factors related to haemoglobin - Download this document for free, or read online. Document in PDF available to download.

BMC Research Notes

, 4:142

First Online: 22 May 2011Received: 01 January 2011Accepted: 22 May 2011DOI: 10.1186-1756-0500-4-142

Cite this article as: Feng, QZ., Zhao, YS. & Li, YF. BMC Res Notes 2011 4: 142. doi:10.1186-1756-0500-4-142

Abstract

BackgroundThe impact of haemoglobin concentrations on clinical outcomes is still a controversial issue. To determine the association between haemoglobin concentrations on admission and clinical outcomes and the related factors, this study was performed in a Chinese hospital.

FindingsWe conducted a retrospective study on 1394 Chinese patients with acute myocardial infarction. Patients were categorized according to the haemoglobin concentration on admission, and data were evaluated to determine whether there was an association between the haemoglobin concentrations on admission and 30-day in-hospital MACEs major cardiovascular events. Patients with hemoglobin values between 141 and 150 g-L were used as the reference, the MACEs increased as hemoglobin concentrations fell below 140 g-L or rose > 150 g-L, with an adjusted OR odds ratio of 5.9695% CI confidence interval 2.00 to 17.68, p = 0.0013, 4.391.37 to 14.08, p = 0.0128, 3.991.46 to 10.92, p = 0.0071, 3.191.27 to 8.05, p = 0.0139, 2.370.94 to 6.01, p = 0.0687, 2.110.66 to 6.74, p = 0.2065, 2.010.60 to 6.68, p = 0.2559 in patients with haemoglobin concentrations <100 g-L, 101-110 g-L, 111-120 g-L, 121-130 g-L, 131-140 g-L, 151-160 g-L, and >160 g-L respectively. Partial correlation analysis showed that age, albumin and creatinine were significantly associated with hemoglobin concentration.

ConclusionsOur results demonstrated that haemoglobin concentration affected MACEs in patients with acute myocardial infarction, and that haemoglobin concentration was associated with age, albumin and creatinine.

List of abbreviationsAMIacute myocardial infarction

Hbhaemoglobin

PCIpercutaneous coronary intervention

ACSacute coronary syndrome

CHDcoronary heart disease

LVEFleft ventricular ejection fraction

MACEsmajor cardiovascular events

ECGElectrocardiogram

CHFcongestive heart failure

ANOVAanalysis of variance

CK-MBcreatine kinase-MB

TCtotal cholesterol

TGtriglyceride

LDL-Clow density lipoprotein cholesterol

HDL-Chigh density lipoprotein cholesterol

CCBcalcium channel blockers

ACEIangiotensin converting enzyme inhibitory

ARBangiotensin receptor blocker.

Electronic supplementary materialThe online version of this article doi:10.1186-1756-0500-4-142 contains supplementary material, which is available to authorized users.

Download fulltext PDF



Author: Quan-Zhou Feng - Yu-Sheng Zhao - Yu-Feng Li

Source: https://link.springer.com/



DOWNLOAD PDF




Related documents