Nutritional treatment of aged individuals with Alzheimer disease living at home with their spouses: study protocol for a randomized controlled trialReport as inadecuate




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Trials

, 13:66

First Online: 24 May 2012Received: 16 January 2012Accepted: 10 April 2012DOI: 10.1186-1745-6215-13-66

Cite this article as: Jyvakorpi, S.K., Puranen, T., Pitkala, K.H. et al. Trials 2012 13: 66. doi:10.1186-1745-6215-13-66

Abstract

BackgroundNutritional status often deteriorates in Alzheimer’s disease AD. Less is known about whether nutritional care reverses malnutrition and its harmful consequences in AD. The aim of this study is to examine whether individualized nutritional care has an effect on weight, nutrition, health, physical functioning, and quality of life in older individuals with AD and their spouses living at home.

MethodsAD patients and their spouses aged >65 years living at home n = 202, 102 AD patients were recruited using central AD registers in Finland. The couples were randomized into intervention and control groups. A trained nutritionist visited intervention couples 4–8 times at their homes and the couples received tailored nutritional care. When necessary, the couples were given protein and nutrient-enriched complementary drinks. All intervention couples were advised to take vitamin D 20 μg-day. The intervention lasted for one year. The couples of the control group received a written guide on nutrition of older people. Participants in the intervention group were assessed every three months. The primary outcome measure is weight change. Secondary measures are the intake of energy, protein, and other nutrients, nutritional status, cognition, caregiver’s burden, depression, health related quality of life and grip strength.

DiscussionThis study provides data on whether tailored nutritional care is beneficial to home-dwelling AD patients and their spouses.

Trial registrationACTRN 12611000018910

KeywordsNutritional intervention Malnutrition Alzheimer disease RCT Nutrient intake AbbreviationsADAlzheimer disease

BMIBody Mass Index

CDRClinical Dementia Rating Scale

HRQOLHealth-related quality of life

IADLInstrumental activities of daily living

MMSEMinimental State Examination

MNAMini Nutritional assessment

NPINeuropsychiatric Inventory.

Electronic supplementary materialThe online version of this article doi:10.1186-1745-6215-13-66 contains supplementary material, which is available to authorized users.

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Author: Satu K Jyvakorpi - Taija Puranen - Kaisu H Pitkala - Merja H Suominen

Source: https://link.springer.com/







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