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Pulmonary alveolar microlithiasis is an extremely rare disease characterizedby intra-alveolar accumulation of calcified spherical particles called microliths,due to a mutation of the gene encoding a membrane transport protein of thealveolar surface. Most patients are asymptomatic at diagnosis. The course ofthe disease is slowly progressive, with development of pulmonary fibrosis andrespiratory failure. The -sandstorm- pattern is the characteristic finding of thisdisease. We report a 39-year-old female presenting with progressive dyspnea. Achest X ray showed ground-glass opacities and a high resolution CT scan showednumerous calcified lung micronodules. A surgical lung biopsy confirmed thediagnosis of pulmonary alveolar microlithiasis.Nota general

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Author: Fernández Ferradas, Cristina; - Salinas, Mauricio; - De Grazia, José Andrés; - Díaz P., Juan Carlos; -

Source: http://repositorio.uchile.cl/



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