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Journal of Translational Medicine

, 11:109

Nutrition and metabolism

Abstract

Idiopathic calcium nephrolithiasis is a multifactorial disease with a complex pathogenesis due to genetic and environmental factors. The importance of social and health effects of nephrolithiasis is further highlighted by the strong tendency to relapse of the disease. Long-term prospective studies show a peak of disease recurrence within 2–3 years since onset, 40-50% of patients have a recurrence after 5 years and more than 50-60% after 10 years. International nutritional studies demonstrated that nutritional habits are relevant in therapy and prevention approaches of nephrolithiasis. Water, right intake of calcium, low intake of sodium, high levels of urinary citrate are certainly important for the primary and secondary prevention of nephrolithiasis.

In this review is discussed how the correction of nutritional mistakes can reduce the incidence of recurrent nephrolithiasis.

KeywordsNephrolithiasis Nutrition Calcium Stones prevention AbbreviationsNADCSodium dependent carrier

DASH dietDietary approaches to stop hypertension

Electronic supplementary materialThe online version of this article doi:10.1186-1479-5876-11-109 contains supplementary material, which is available to authorized users.

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Author: Elena Dogliotti - Giuseppe Vezzoli - Antonio Nouvenne - Tiziana Meschi - Annalisa Terranegra - Alessandra Mingione - Caterin

Source: https://link.springer.com/







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