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Reference: Wertheim, HF, Nguyen, HN, Taylor, W et al., (2009). Streptococcus suis, an important cause of adult bacterial meningitis in northern Vietnam. PloS one, 4 (6), Article: e5973.Citable link to this page:

 

Streptococcus suis, an important cause of adult bacterial meningitis in northern Vietnam.

Abstract: BACKGROUND: Streptococcus suis can cause severe systemic infection in adults exposed to infected pigs or after consumption of undercooked pig products. S. suis is often misdiagnosed, due to lack of awareness and improper testing. Here we report the first fifty cases diagnosed with S. suis infection in northern Viet Nam. METHODOLOGY/PRINCIPAL FINDINGS: In 2007, diagnostics for S. suis were set up at a national hospital in Hanoi. That year there were 43 S. suis positive cerebrospinal fluid samples, of which S. suis could be cultured in 32 cases and 11 cases were only positive by PCR. Seven patients were blood culture positive for S. suis but CSF culture and PCR negative; making a total of 50 patients with laboratory confirmed S. suis infection in 2007. The number of S. suis cases peaked during the warmer months. CONCLUSIONS/SIGNIFICANCE: S. suis was commonly diagnosed as a cause of bacterial meningitis in adults in northern Viet Nam. In countries where there is intense and widespread exposure of humans to pigs, S. suis can be an important human pathogen.

Peer Review status:Peer reviewedPublication status:PublishedVersion:Publisher's version Funder: Wellcome Trust   Funder: South East Asian Infectious Disease Clinical Research Network   Notes:Copyright 2009 Wertheim et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Bibliographic Details

Publisher: Public Library of Science

Publisher Website: http://www.plos.org

Journal: PloS onesee more from them

Publication Website: http://www.plosone.org

Issue Date: 2009

pages:Article: e5973Identifiers

Urn: uuid:907ecf1f-3742-4732-a719-2ac8adb6b2b7

Source identifier: 34767

Eissn: 1932-6203

Doi: https://doi.org/10.1371/journal.pone.0005973

Issn: 1932-6203 Item Description

Type: Journal article;

Language: eng

Version: Publisher's versionKeywords: Animals Humans Streptococcus suis Meningitis, Bacterial Polymerase Chain Reaction Sequence Analysis, DNA Adolescent Adult Aged Middle Aged Vietnam Female Streptococcal Infections Swine Male Tiny URL: pubs:34767

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Author: Wertheim, HF - institutionUniversity of Oxford Oxford, MSD, Clinical Medicine, Tropical Medicine - - - Nguyen, HN - - - Taylor, W

Source: https://ora.ox.ac.uk/objects/uuid:907ecf1f-3742-4732-a719-2ac8adb6b2b7



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