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Reference: Operario, D, Underhill, K, Chuong, C et al., (2011). HIV infection and sexual risk behaviour among youth who have experienced orphanhood: systematic review and meta-analysis. Journal of the International AIDS Society, 14, 25.Citable link to this page:

 

HIV infection and sexual risk behaviour among youth who have experienced orphanhood: systematic review and meta-analysis.

Abstract: Background: Previous research has suggested that orphaned children and adolescents might have elevated risk for HIV infection. We examined the state of evidence regarding the association between orphan status and HIV risk in studies of youth aged 24 years and younger.Methods: Using systematic review methodology, we identified 10 studies reporting data from 12 countries comparing orphaned and non-orphaned youth on HIV-related risk indicators, including HIV serostatus, other sexually transmitted infections, pregnancy and sexual behaviours. We meta-analyzed data from six studies reporting prevalence data on the association between orphan status and HIV serostatus, and we qualitatively summarized data from all studies on behavioural risk factors for HIV among orphaned youth. Results:Meta-analysis of HIV testing data from 19,140 participants indicated significantly greater HIV seroprevalence among orphaned (10.8%) compared with non-orphaned youth (5.9%) (odds ratio = 1.97; 95% confidence interval = 1.41-2.75). Trends across studies showed evidence for greater sexual risk behaviour in orphaned youth. Conclusions:Studies on HIV risk in orphaned populations, which mostly include samples from sub-Saharan Africa, show nearly two-fold greater odds of HIV infection among orphaned youth and higher levels of sexual risk behaviour than among their non-orphaned peers. Interventions to reduce risk for HIV transmission in orphaned youth are needed to address the sequelae of parental illness and death that might contribute to sexual risk and HIV infection.

Peer Review status:Peer reviewedPublication status:PublishedVersion:Publisher's version Funder: Leverhulme Trust   Funder: John Fell Fund   Funder: National Institutes of Health   Notes:© 2011 Operario et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Bibliographic Details

Publisher: BioMed Central

Publisher Website: http://www.biomedcentral.com/

Journal: Journal of the International AIDS Societysee more from them

Publication Website: http://www.jiasociety.org/

Issue Date: 2011-1

Article Number:ARTN 25

pages:25Identifiers

Urn: uuid:cf294f78-bc0a-4334-a964-a42e1f2b398c

Source identifier: 141490

Eissn: 1758-2652

Doi: https://doi.org/10.1186/1758-2652-14-25

Issn: 1758-2652 Item Description

Type: Journal article;

Language: eng

Version: Publisher's versionKeywords: Humans Pregnancy Complications, Infectious HIV Infections Prevalence Risk-Taking Sexual Behavior Pregnancy Adolescent Adult Child Female Child, Orphaned Young Adult Tiny URL: pubs:141490

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Author: Operario, D - - - Underhill, K - - - Chuong, C - - - Cluver, L - institutionUniversity of Oxford Oxford, SSD, Social Policy and I

Source: https://ora.ox.ac.uk/objects/uuid:cf294f78-bc0a-4334-a964-a42e1f2b398c



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