The harmonization process to set up and maintain an operational biological and physical retrospective dosimetry network : QA QM applied to the RENEB networkReport as inadecuate




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(2017)INTERNATIONAL JOURNAL OF RADIATION BIOLOGY.93(1).p.81-86 Mark abstract Purpose: The European Network of Biological and Physical Retrospective Dosimetry ‘RENEB’ has contributed to European radiation emergency preparedness. To give homogeneous dose estimation results, RENEB partners must harmonize their processes. Materials and methods: A first inter-comparison focused on biological and physical dosimetry was used to detect the outliers in terms of dose estimation. Subsequently, trainings were organized to improve both tools dose estimation. A second inter-comparison was performed to validate training efficiency. Simultaneously, based on ISO standards, a QA&QM manual on all dosimetry assays was produced which states a common basis and harmonized procedures for each assay. The evaluation of the agreement of RENEB partners to follow the QA&QM manual was performed through a questionnaire. The integration of new members into the network was carried out in the same way, whatever the assays.Results: The training courses on biological and physical dosimetry were judged to be successful because most of the RENEB members’ dose estimates improved in the second inter-comparison. The QA&QM manual describes the consensus for the minimum requirements and the performance criteria for both dosimetry assays. The questionnaire revealed that the whole network capacity currently can manage between 15 and 3800 samples once.Conclusion: The methodology used to harmonize all dosimetry practice within the network RENEB was highly successful. The network is operational to manage a mass casualty radiation accident for immediate dose assessment.

Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-8113612



Author: Eric Gregoire, Liz Ainsbury, Leonardo Barrios, Céline Bassinet, Paola Fattibene, Ulrike Kulka, Ursula Oestreicher, Gabriel Pantel

Source: https://biblio.ugent.be/publication/8113612



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