Is there an error correcting code in the base sequence in DNA.Report as inadecuate


 Is there an error correcting code in the base sequence in DNA.


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Type of Resource: text

Genre: article

Issuance: single unit

Date Issued: 1996-09

Publisher: The Biophysical Society

Language(s): English

Identifier: FADT165441 (IID), 165441 (digitool), fau:2603 (fedora), 0006-3495/96/09/1539/06 (Biophysical Society)

FAU Department/College: Department of Psychology Charles E. Schmidt College of Science

Note(s): Modern methods of encoding information into digital form include error check digits that are functions of the other information digits. When digital information is transmitted, the values of the error check digits can be computed from the information digits to determine whether the information has been received accurately. These error correcting codes make it possible to detect and correct common errors in transmission. The sequence of bases in DNA is also a digital code consisting of four symbols: A, C, G, and T. Does DNA also contain an error correcting code? Such a code would allow repair enzymes to protect the fidelity of nonreplicating DNA and increase the accuracy of replication. If a linear block error correcting code is present in DNA then some bases would be a linear function of the other bases in each set of bases. The authors have developed an efficient procedure to determine whether such an error correcting code is present in the base sequence. The article illustrates the use of this procedure by using it to analyze the Iac operon and the gene for cytochrome c. These genes do not appear to contain such a simple error correcting code.This manuscript is a version of an article published in Biophysical Journal v. 71, no. 3 (September 1996) p. 1539-1544 http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1233620

Subject(s): Biophysics--ResearchDNAGeneticsDNA Repair--geneticsDNA--Analysis--Mathematical modelsGenetic code

Persistent Link to This Record: http://purl.flvc.org/fau/165441

Restrictions on Access: ©1996 The Biophysical Society

Owner Institution: FAU



Author: Liebovitch, Larry S., creator Levine, Leo, creator Tao, Yi, creator Todorov, Angelo T., creator

Source: http://fau.digital.flvc.org/islandora/object/fau%3A2603



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