Efeitos da idade sobre as frequências de micronúcleos e alterações nucleares degenerativas Report as inadecuate




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Antônio de Oliveira Costa Neto ; Eneida de Moraes Marcílio Cerqueira ; José Roberto Cardoso Meireles ;Revista Brasileira de Geriatria e Gerontologia 2016, 19 4

Author: Gregory Alves Ferraz

Source: http://www.redalyc.org/articulo.oa?id=403847457007_2


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Revista Brasileira de Geriatria e Gerontologia ISSN: 1809-9823 revistabgg@gmail.com Universidade do Estado do Rio de Janeiro Brasil Alves Ferraz, Gregory; de Oliveira Costa Neto, Antônio; de Moraes Marcílio Cerqueira, Eneida; Cardoso Meireles, José Roberto Efeitos da idade sobre as frequências de micronúcleos e alterações nucleares degenerativas Revista Brasileira de Geriatria e Gerontologia, vol.
19, núm.
4, julio-agosto, 2016, pp.
627634 Universidade do Estado do Rio de Janeiro Rio de Janeiro, Brasil Available in: http:--www.redalyc.org-articulo.oa?id=403847457007 How to cite Complete issue More information about this article Journals homepage in redalyc.org Scientific Information System Network of Scientific Journals from Latin America, the Caribbean, Spain and Portugal Non-profit academic project, developed under the open access initiative http:--dx.doi.org-10.1590-1809-98232016019.150155 Original Articles Effects of age on the frequency of micronuclei and degenerative nuclear abnormalities Gregory Alves Ferraz1 Antônio de Oliveira Costa Neto1 Eneida de Moraes Marcílio Cerqueira1 José Roberto Cardoso Meireles1 Abstract The effects of aging, gender and lifestyle factors on inducing chromosomal damage (micronuclei) and nuclear degenerative changes were assessed using the micronucleus test on exfoliated cells of the oral mucosa.
The sample included 80 healthy subjects divided into four groups according to age and gender: men and women aged 19-29 years (M19, W19) and men and women aged over sixty years (M60, W60).
An interview questionnaire was used to characterize the sample and to determine an index reflecting lifestyle (HLI).
The frequency of micronuclei and nuclear degenerative changes was significantly higher among the elderly ( p 0.001) and did not differ by gender among young people ( p 0.05).
The occurrence of micronuclei was similar among elderly men and women ( p 0.10), but karyorrhexis and karyolysis were more frequent among men ( p 0...





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