On empirical processes for Quantitative Trait Locus mapping under the presence of a selective genotyping and an interference phenomenonReport as inadecuate




On empirical processes for Quantitative Trait Locus mapping under the presence of a selective genotyping and an interference phenomenon - Download this document for free, or read online. Document in PDF available to download.

1 LSProba - Laboratoire de Statistiques et Probabilités

Abstract : We consider the likelihood ratio test LRT process related to the test of the absence of QTL i.e. a gene with quantitative effect on a trait on the interval 0,T representing a chromosome. The originality is twofold. We consider a selective genotyping and an interference phenomenon. We show that, under the null hypothesis and contiguous alternatives, the LRT process is asymptotically the square of a -linear interpolated and normalized Gaussian process -. We prove that we have to genotype symmetrically and that the threshold is exactly the same as in the situation without selective genotyping and without interference.





Author: Charles-Elie Rabier -

Source: https://hal.archives-ouvertes.fr/



DOWNLOAD PDF




Related documents