Signal enhancement of electrochemical biosensors via direct electrochemical oxidation of silver nanoparticle labels coated with zwitterionic polymersReport as inadecuate




Signal enhancement of electrochemical biosensors via direct electrochemical oxidation of silver nanoparticle labels coated with zwitterionic polymers - Download this document for free, or read online. Document in PDF available to download.

* Corresponding author 1 SIMM - Sciences et Ingénierie de la Matière Molle 2 LPPI - Laboratoire de Physico-chimie des Polymères et des Interfaces

Abstract : A new electrochemical label has been developed, which is made up of silver nanoparticles AgNPs coated with a mixture of zwitterionic and biotinylated zwitterionic polymers. These polymers improve colloidal stability in physiological medium and ensure biorecognition while direct electrochemical oxidation of silver nanoparticles strongly enhances the detection signal. The resulting hybrid nanomaterials are used as labels in the electrochemical sensing of avidin using sandwich assays elaborated using the biotin-avidin biorecognition system.





Author: R Geagea - Pierre-Henri Aubert - Philippe Banet - Nicolas Sanson -

Source: https://hal.archives-ouvertes.fr/



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