Spectroscopic and Imaging Characteristics of Pigmented Non-Melanoma Skin Cancer and Melanoma in Patients with Skin Phototypes III and IVReport as inadecuate




Spectroscopic and Imaging Characteristics of Pigmented Non-Melanoma Skin Cancer and Melanoma in Patients with Skin Phototypes III and IV - Download this document for free, or read online. Document in PDF available to download.

Oncology and Therapy

, Volume 4, Issue 2, pp 315–331

First Online: 12 December 2016Received: 05 August 2016

Abstract

IntroductionNon-melanoma skin cancer is the most common malignancy worldwide. Differentiating between malignant and benign skin tumors, however, can be challenging. As a result, various auxiliary tools have been developed to aid in the diagnosis of cutaneous neoplasms. Here, skin tumors were investigated through analysis of their digital image histograms and spectroscopic response under ultraviolet UV and white light-emitting diodes LEDs.

MethodsFifty tumoral lesions were spectroscopically and histologically studied. For optical studies, UV at 375 nm and white LEDs were used to illuminate the lesions. Commercial cameras were used for imaging, and a miniature spectrometer with a bifurcated optical fiber was used for spectroscopic measurements.

ResultsIn this study, the intensity histograms of the images taken under white and UV illumination and the spectroscopic response under white light showed clear differences between pigmented basal cell carcinoma BCC, intradermal melanocytic nevus IDN, and melanoma lesions for skin phototypes III and IV. However, there was little difference in their spectroscopic response to the UV LED.

ConclusionWe found differences in the intensity and shape of diffuse reflectance spectra of pigmented BCC, IDN, and melanoma lesions in patients with skin phototypes III and IV. Also, images taken under UV and white light were helpful for differentiation of these pigmented lesions. Additional research is needed to ascertain the clinical utility of these tools for skin cancer diagnosis.

KeywordsDigital images Melanoma Skin cancer Spectroscopy Enhanced Content To view enhanced content for this article go to http:-www.medengine.com-Redeem-4627F0603B3AA17A.

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Author: Stefanie Arroyo-Camarena - Judith Domínguez-Cherit - Lorena Lammoglia-Ordiales - Diego A. Fabila-Bustos - Abraham Escobar-P

Source: https://link.springer.com/



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