Coronary arterial dynamics computation with medical-image-based time-dependent anatomical models and element-based zero-stress state estimatesReport as inadecuate




Coronary arterial dynamics computation with medical-image-based time-dependent anatomical models and element-based zero-stress state estimates - Download this document for free, or read online. Document in PDF available to download.

Computational Mechanics

, Volume 54, Issue 4, pp 1047–1053

First Online: 03 July 2014Received: 01 June 2014Accepted: 15 June 2014

Abstract

We propose a method for coronary arterial dynamics computation with medical-image-based time-dependent anatomical models. The objective is to improve the computational analysis of coronary arteries for better understanding of the links between the atherosclerosis development and mechanical stimuli such as endothelial wall shear stress and structural stress in the arterial wall. The method has two components. The first one is element-based zero-stress ZS state estimation, which is an alternative to prestress calculation. The second one is a -mixed ZS state- approach, where the ZS states for different elements in the structural mechanics mesh are estimated with reference configurations based on medical images coming from different instants within the cardiac cycle. We demonstrate the robustness of the method in a patient-specific coronary arterial dynamics computation where the motion of a thin strip along the arterial surface and two cut surfaces at the arterial ends is specified to match the motion extracted from the medical images.

KeywordsCoronary arterial dynamics Time-dependent anatomical model Medical-image-based data Coronary atherosclerosis  Element-based zero-stress state estimate Mixed zero-stress state  Download fulltext PDF



Author: Kenji Takizawa - Ryo Torii - Hirokazu Takagi - Tayfun E. Tezduyar - Xiao Y. Xu

Source: https://link.springer.com/



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