Complete genome analysis of a rare human G3P9 rotavirus posing as an AU-1 like strainReport as inadecuate




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, 2:569

Biomedical and Life Sciences

Abstract

BackgroundWe performed phylogenetic and sequence analysis by Basic Local Alignment Search Tool BLAST of a complete Human Rotavirus HRV genome isolated from a hospitalized child with acute gastroenteritis in Thailand.

FindingsThe results indicated an uncommon strain characterized by multiple re-assortments in the VP3, VP4, VP6, NSP1, NSP4 and NSP5 genes. The uncommon strain is genotype G3-P9-I3-R3-C3-M3-A3-N3-T3-E3-H6, which displays aspects of the AU-1, FRV-1 and corresponds to the feline-canine prototype G3P9 strain.

ConclusionsThe results suggested that nearly all the eleven gene segments of G3P9 RVA strain CU365 might have originated from feline-canine RVAs Rotavirus A.

KeywordsHuman rotavirus HRV Uncommon strain AU-1 like strain G3P9 Electronic supplementary materialThe online version of this article doi:10.1186-2193-1801-2-569 contains supplementary material, which is available to authorized users.

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Author: Apiradee Theamboonlers - Ornwalan Maiklang - Thanunrat Thongmee - Thaweesak Chieochansin - Viboonsuk Vuthitanachot - Yong Po

Source: https://link.springer.com/



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