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Diagnostic Pathology

, 8:206

First Online: 11 December 2013Received: 22 September 2013Accepted: 28 November 2013

Abstract

BackgroundMucinous tubular and spindle cell carcinoma of kidney MTSCC-K is a rare variant of renal tumor. The current data show most of MTSCCs are of low malignant potential and rare cases metastatic to lymph nodes have been reported; however, the recorded computed tomography CT and follow up data are limited.

Material and methodIn the present study, we retrospectively analyzed CT and clinicopathological data of eight patients with renal MTSCC-K.

ResultsA total of eight cases, including six females and two males, were included in this analysis with a mean age of 48.4 range 25 to 81 years. Mean tumor size was 4.2 range 2.5 to 10.0 cm. Preoperative CT demonstrated that all tumors were slightly enhanced on both corticomedullary and nephrographic phase, which was different from many other renal cell carcinomas. Three of them were treated with open radical nephrectomy, three with laparoscopic radical nephrectomy and the other two with laparoscopic partial nephrectomy. No postoperative therapy was applied. Patients were followed up for 15 to 64 months and there was no evidence of recurrence and metastasis.

ConclusionsThe MTSCC-K has special clinicopathological characteristics, low degree of malignancy and relative good prognosis. The diagnosis mainly depends on the histopathological examination and CT may help to differentiate with papillary renal cell carcinoma. Surgical treatment is recommended and additional therapies are not necessary.

Virtual slidesThe virtual slides for this article can be found here: http:-www.diagnosticpathology.diagnomx.eu-vs-8435581771088249.

KeywordsRenal cell carcinoma Mucinous tubular and spindle cell carcinoma Computed tomography AbbreviationsMTSCC-KMucinous tubular and spindle cell carcinoma of the kidney

RCCRenal cell carcinoma

CTComputed tomography

CMPCorticomedullary phase

NPNephrographic phase

HUHounsfield units.

Electronic supplementary materialThe online version of this article doi:10.1186-1746-1596-8-206 contains supplementary material, which is available to authorized users.

Xiao-rong Wu, Yong-hui Chen contributed equally to this work.

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Author: Xiao-rong Wu - Yong-hui Chen - Jian-jun Sha - Ling Zhao - Ji-wei Huang - Juan-jie Bo - Dong-ming Liu - Yi-ran Huang

Source: https://link.springer.com/







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