Chronic Cough in Musculoskeletal disorders: Using high resolution oesophageal manometry in search of an AetiologyReport as inadecuate




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Cough

, 8:6

First Online: 28 September 2012Received: 28 May 2012Accepted: 07 September 2012

Abstract

Chronic cough is a common symptom carrying significant morbidity which can occur as a result of oesophageal dysmotility. Here we report 2 patients with musculoskeletal disease presenting with chronic cough to our tertiary cough clinic. Prior to referral both patients had been extensively investigated to determine the basis of their cough, with no cause found. Oesophageal studies, using high resolution oesophageal manometry, demonstrated oesophageal dysmotility with consequent airway reflux. Anti-reflux therapy resulted in a good response in both patients. These are the first reports of the recently developed technique of high resolution manometry aiding the diagnosis of chronic cough. This technique may provide important clues into aetiological mechanism in patients with conditions predisposing to reflux into the airways.

KeywordsChronic cough Airway reflux Ehlers-Danlos Dermatomyositis AbbreviationsGORDGastro-oesophageal reflux disease

LOSLower oesophageal sphincter

UOSUpper oesophageal sphincter

TIATransient ischaemic attack

PPIProton-pump inhibitor.

Electronic supplementary materialThe online version of this article doi:10.1186-1745-9974-8-6 contains supplementary material, which is available to authorized users.

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Author: Sega Pathmanathan - Jaymin B Morjaria - Warren Jackson - Alyn H Morice

Source: https://link.springer.com/







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