The global epidemiology of clonorchiasis and its relation with cholangiocarcinomaReport as inadecuate




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Infectious Diseases of Poverty

, 1:4

Co-infection and SyndemicsHealth Systems Research for Infectious Diseases of Poverty

Abstract

This paper reviews the epidemiological status and characteristics of clonorchiasis at global level and the etiological relationship between Clonorchis sinensis infection and cholangiocarcinoma CCA. A conservative estimation was made that 15 million people were infected in the world in 2004, of which over 85% distributed in China. The epidemiology of clonorchiasis is characterized by rising trend in its prevalence, variability among sexes and age, as well as endemicity in different regions. More data indicate that C. sinensis infection is carcinogenic to human, and it is predicted that nearly 5 000 CCA cases attributed to C. sinensis infection may occur annually in the world decades later, with its overall odds ratio of 4.47. Clonorchiasis is becoming one major public health problem in east Asia, and it is worthwhile to carry out further epidemiological studies.

KeywordsClonorchiasis Clonorchis sinensis Epidemiology Cholangiocarcinoma Odds ratio Electronic supplementary materialThe online version of this article doi:10.1186-2049-9957-1-4 contains supplementary material, which is available to authorized users.

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Author: Men-Bao Qian - Ying-Dan Chen - Song Liang - Guo-Jing Yang - Xiao-Nong Zhou

Source: https://link.springer.com/



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